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Pkr Inhibitor. Purity Quality Control Choose Selective PKR Inhibitors. PKR Inhibitor protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress. PKR is phosphorylated and activated by dsRNA and polyIC 1 and contributes to the induction of type I interferons such as IFN-β which can further increase its expression 2. This small moleculeinhibitor is primarily used for Phosphorylation Dephosphorylation applications.
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C16 binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM. PKR is phosphorylated and activated by dsRNA and polyIC 1 and contributes to the induction of type I interferons such as IFN-β which can further increase its expression 2. 5 matches found for PKR inhibitor 2-Aminopurine. PKR inhibitor C16 prevents apoptosis and IL-1β production in an acute excitotoxic rat model with a. PKR-inhibitor binds efficiently with human microtubule affinity-regulating kinase 4 MAPmicrotubule affinity-regulating kinase 4 MARK4 plays a central role in the cellular physiology and it is inseparably linked with many human diseases including cancer diet induced obesity type2 diabetes and neurodegenerative disorders. PKR inhibitor 2-Aminopurine Compare Products.
C16 also known as GW-506033X or PKR Inhibitor.
The alpha subunit of the eukaryotic initiation factor 2 is phosphorylated by the PKR which is an interferon-induced serinethreonine protein. The alpha subunit of the eukaryotic initiation factor 2 is phosphorylated by the PKR which is an interferon-induced serinethreonine protein. The specific PKR inhibitor C16 has been previously demonstrated to exert a neuroprotective role in adult brain injuries. PKR Inhibitor CAS 608512-97-6 is a potent ATP-binding site directed PKR inhibitor that blocks RNA-induced PKR autophosphorylation IC50 210 nM. Specific double-stranded RNA-dependent protein kinase PKR inhibitor. It also prevents phosphorylation of Fas-associated protein with a death domain FADD in neuroblastoma cells preventing FADD-dependent activation of.
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PKR Inhibitor CAS 608512-97-6 is a potent ATP-binding site directed PKR inhibitor that blocks RNA-induced PKR autophosphorylation IC50 210 nM. The activity of double-stranded RNA-activated protein kinase PKR is altered by viral infection as well as by various neuropathologies. Prevents PKR-induced neuronal loss in vivo. Purity Quality Control Choose Selective PKR Inhibitors. PKR Inhibitor is an oxindoleimidazole derivative that binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM3 PKR Inhibitor protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress.
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Prevents PKR-induced neuronal loss in vivo. The specific PKR inhibitor C16 has been previously demonstrated to exert a neuroprotective role in adult brain injuries. 1 Product Result. This small moleculeinhibitor is primarily used for Phosphorylation Dephosphorylation applications. GW-506033X protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress.
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12 A primary phosphorylation target of PKR is eukaryotic initiation factor 2 subunit α eIF2α blocking translation and driving apoptosis. PERK Inhibitor I GSK2606414 - CAS 1337531-89-1 - Calbiochem. Rescue PKR-dependent translation block. 3 PKR Inhibitor is an oxindoleimidazole derivative that binds the ATP-binding site of PKR and blocks autophosphorylation with an IC 50 value. Prevents PKR-induced neuronal loss in vivo.
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PKR Inhibitor is an oxindoleimidazole derivative that binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM3 PKR Inhibitor protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress. PKR Inhibitor is an oxindoleimidazole derivative that binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM3 PKR Inhibitor protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress. 1 Product Result. Prevents PKR-induced neuronal loss in vivo. The activity of double-stranded RNA-activated protein kinase PKR is altered by viral infection as well as by various neuropathologies.
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The RNA-dependent protein kinase PKR inhibitor is an imidazolo-oxindole derivative that has been shown to inhibit RNA-induced PKR autophosphorylation and rescue PKR-dependent translation block. This small moleculeinhibitor is primarily used for Phosphorylation Dephosphorylation applications. The specific PKR inhibitor C16 has been previously demonstrated to exert a neuroprotective role in adult brain injuries. Rescue PKR-dependent translation block. However there is no recent study availa.
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PKR Inhibitor Negative Control C15H8Cl3NO2 CID 16760619 - structure chemical names physical and chemical properties classification patents literature biological activities safetyhazardstoxicity. PKR Inhibitor CAS 608512-97-6 is a potent ATP-binding site directed PKR inhibitor that blocks RNA-induced PKR autophosphorylation IC50 210 nM. 5 matches found for PKR inhibitor 2-Aminopurine. PKR Inhibitor protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress. C16 binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM.
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Select up to 4 products. BACKGROUND Brain injuries induced by hypoxia-ischemia in neonates contribute to increased mortality and. The PKR Inhibitor also referenced under CAS 608512-97-6 controls the biological activity of PKR. PERK Inhibitor I GSK2606414 - CAS 1337531-89-1 - Calbiochem. 1 Product Result.
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PERK Inhibitor I GSK2606414 - CAS 1337531-89-1 - Calbiochem. Inhibits apoptotic PKReIF2α signaling pathway in vivo. PKR Inhibitor CAS 608512-97-6 is a potent ATP-binding site directed PKR inhibitor that blocks RNA-induced PKR autophosphorylation IC50 210 nM. The specific PKR inhibitor C16 has been previously demonstrated to exert a neuroprotective role in adult brain injuries. Prevents PKR-induced neuronal loss in vivo.
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C16 binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM. PKR-IN-C16 imoxin C16 Imidazolo-oxindole PKR inhibitor C16 is a specific inhibitor of RNA-dependent protein kinase PKR Protein Kinase R EIF2AK2. PKR inhibitor C16 prevents apoptosis and IL-1β production in an acute excitotoxic rat model with a. PERK Inhibitor I GSK2606414 - CAS 1337531-89-1 - Calbiochem. Select up to 4 products.
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Rescue PKR-dependent translation block. PKR-inhibitor binds efficiently with human microtubule affinity-regulating kinase 4 MAPmicrotubule affinity-regulating kinase 4 MARK4 plays a central role in the cellular physiology and it is inseparably linked with many human diseases including cancer diet induced obesity type2 diabetes and neurodegenerative disorders. Inhibits apoptotic PKReIF2α signaling pathway in vivo. It also prevents phosphorylation of Fas-associated protein with a death domain FADD in neuroblastoma cells preventing FADD-dependent activation of. Please select more than one item to compare.
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GW-506033X protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress. Please select more than one item to compare. Inhibits apoptotic PKReIF2α signaling pathway in vivo. Advanced Search Structure Search. 1 Product Result.
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GW-506033X protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress. BACKGROUND Brain injuries induced by hypoxia-ischemia in neonates contribute to increased mortality and. PERK Inhibitor I GSK2606414 - CAS 1337531-89-1 - Calbiochem. Neuroprotective antitumor and anti-inflammatory agent. PKR-IN-C16 prevents apoptosis and IL-1β production in an acute excitotoxic rat model with a neuroinflammatory component.
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3 PKR Inhibitor is an oxindoleimidazole derivative that binds the ATP-binding site of PKR and blocks autophosphorylation with an IC 50 value. Prevents PKR-induced neuronal loss in vivo. PKR-IN-C16 prevents apoptosis and IL-1β production in an acute excitotoxic rat model with a neuroinflammatory component. The specific PKR inhibitor C16 has been previously demonstrated to exert a neuroprotective role in adult brain injuries. PKR Inhibitor Negative Control C15H8Cl3NO2 CID 16760619 - structure chemical names physical and chemical properties classification patents literature biological activities safetyhazardstoxicity.
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